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A Peer-Reviewed Journal Published Bimonthly by a Non-Profit Publisher |
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Print ISSN: 1816-0735 Online ISSN: 1817-4256AIM & SCOPE Journal of Cancer Molecules publishes peer-reviewed reviews and original papers concerned with basic research and clinical practice in the molecular aspects of cancer. Research areas covered in the Journal include: cancer genomics and proteomics, tumor markers and clinical molecular correlates, molecular carcinogenesis, structures of cancer-related molecules, development of therapeutic molecules, and molecular pharmacology. Specially, the Journal encourages the reports of clinical therapies against molecular targets. |
This journal is indexed/covered by: CAplus, CEPS, TEPS, Sirus, Scopus, EMBASE, Google Scholar, DOAJ, etc. ¡@ In this Journal..... miRNAs in human cancers [4(3): 79-89][3(5): 133-138] Cancer as a "Mitochondriopathy" Cys-Oxidation [3(2): 37-43 / 2(1): 9-16]: Emerging roles of cys-oxidation in regulating proteins involved in cell signaling and tumor malignancy. Potential Target for Anti-Cancer Therapy: Cathepsin S inhibitors summarized in 3(1): 5-14 Online movies: Volume 2 Number 4 / Online supplement (Movie) Tumor-Associated Macrophages Induce Vascular Endothelial Cell Capillary Tube and Network Formation Volume 2 Number 3 / Online supplement (Movie) Tumor-Associated Macrophages: Frontiersmen of Tumor Spreading ¡@ For more melanoma research information, please go to The Melanoma Molecular Map Project (MMMP), an open-access multi-database dedicated to the research on melanoma biology and therapy....
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In Volume 5 Number 1: Heparins are commonly administered to cancer patients for the treatment and prophylaxis of thromboembolic events. Several clinical trials have demonstrated an improved survival of cancer patients who were administered low-molecular-weight heparins. This improved survival was independent of the anti-thrombotic efficacy; moreover, it was not the result of the inhibition of primary tumor growth, but rather the prevention of cancer cell spreading through metastases. The review article [5(1): 3-8] discusses the most likely mechanisms by which heparins and heparin derivatives attenuate cancer metastases, including a restraint of P- and L-selectin-mediated interactions of platelets with circulating neoplastic cells, a modulation of the chemokine CXCL12/CXCR4 axis, an inhibition of heparanase activity, and the inhibition of angiogenesis in the tumor¡K. |
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Copyright 2009 MedUnion Press J If you have any question about this Journal, please contact: ¡@ If you have any question in submitting paper, please contact: ¡@ If you have any question about the reviewing and editorial process, please contact: ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@ ¡@
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Review Article |
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Anti-Metastatic Activities of Heparins / 5(1): 3-8 / by Marian Simka and Tomasz Urbanek ¡@ |
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Research Papers |
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ATM Phosphorylation Kinetics as a Biological Reporter of Cellular Radiosensitivity / 5(1): 9-14 / by Amir Lavaf, Shibo Fu, Sheila Peters, Yen-Nien Hou, Barry S. Rosenstein, and Johnny Kao Characterization of Retinoid Receptor-Induced Gene-1 Gene and Its Relationship to SH3 Domain GRB2-Like Endophilin B2 Gene / 5(1): 15-19 / by Baoxiang Guan, Hao Li, Yulong Chen, Ashraful Hoque, and Xiao-Chun Xu Differential Induction of Apoptosis by Apple Procyanidins in TRAIL-Sensitive Human Colon Tumor Cells and Derived TRAIL-Resistant Metastatic Cells / 5(1): 21-30 / by Maria-Elena Maldonado-Celis, Souad Bousserouel, Francine Gossé, Carole Minker, Annelise Lobstein, and Francis Raul ¡@ |
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Recently Published Papers |
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Endothelins as a Potential Target for Anticancer Therapy / 4(6): 163-167 / by Deimante Tamkus, Anas Al-Janadi, Gregory Fink, Ganapathy Krishnan, and Nikolay V. Dimitrov ¡@ Differential Regulation of Growth Factors and Matrix Metalloproteinase-1 by Estrogen, Progesterone, and Tamoxifen in Normal and Cancerous Endometrial cells / 4(6): 169-173 / by Neena Philips, Michael Tahir, Jennifer Stellatella, Kelly Stephan, Joshua Givant, Linda Zhou, Angelica Costa, and May Taw ¡@ Prolonged Antiresorptive Treatment of Lytic Prostate Cancer Xenografts in Mouse Bone Results in Tumor Necrosis / 4(6): 175-181 / by J. M. Blair, J. R. K. Modzelewski, L. A. Perryman, P. J. Russell, M. J. Seibel, and C. R. Dunstan ¡@ Modulation of Cyclophosphamide-Induced Cellular Toxicity by Diphenylmethyl Selenocyanate In Vivo, an Enzymatic Study / 4(6): 183-189 / by Pramita Chakraborty, Ugir Hossain Sk, Nabendu Murmu, Jayanta Kumar Das, Smarajit Pal, and Sudin Bhattacharya ¡@ Advancement in Mammary Stem Cell Research / 4(5): 131-138 / by Taraneh Esmailpour and Taosheng Huang ¡@ Inhibition of Nuclear Accumulation of Phosphorylated ERK by Tropomyosin-1¡VMediated Cytoskeletal Reorganization / 4(5): 139-144 / by Shantaram Bharadwaj, Girish Vasanth, Laura Masuelli, Ruchi Thanawala, and G. L. Prasad ¡@ Role of Melanoma Secreted Thrombospondin-1 on Induction of Immunosuppressive Regulatory T Cells through CD47 / 4(5): 145-152 / by Joel M. Baumgartner, Brent E. Palmer, Anirban Banerjee, and Martin D. McCarter ¡@ Hypoxia-Inducible Factor-1alpha mRNA and Protein Levels in Renal Cell Carcinoma / 4(5): 153-157 / by Anders Lidgren, Anders Bergh, Kjell Grankvist, Gudrun Lindh, and Börje Ljungberg ¡@ Multi-Chaperones-Interactors Network in Mitochondria (MtCIN): Its Role in Carcinogenesis and Methodology of Analysis / 4(4): 99-108 / by Anna M. Czarnecka, Jerzy S. Czarnecki, Anna Ribbene, and Francesco Cappello ¡@ Eurycomanone Induces Apoptosis through the Up-Regulation of p53 in Human Cervical Carcinoma Cells / 4(4): 109-115 / by Nurkhasanah Mahfudh and Azimahtol Hawariah Lope Pihie ¡@ Screening of Trichostatin Analogues Based on Cellular Potency in the Murine Multiple Myeloma 5T33MM Model / 4(4): 117-121 / by Sarah Deleu, Joanna Fraczek, Aneta Lukaszuk, Tatyana Doktorova, Dirk Tourwé, Albert Geerts, Ben Van Camp, Tamara Vanhaecke, Vera Rogiers, and Karin Vanderkerken ¡@ Methylation Profiles of hMLH1 Proximal Promoter in Colorectal Tumor Progression / 4(4): 123-127 / by Romain Marignol, Jeanne Ramos, Pascal Pujol, Thierry Maudelonde, and Jean-Marc Rey ¡@ RNA Interference ¡V Regulations and Application in Oncology / 4(3): 67-77 / by Dragomira Nikolova and Draga Toncheva ¡@ Great Potential of MicroRNA in Cancer Stem Cell / 4(3): 79-89 / by MicroGene H. P. Xia ¡@ Abnormal Expression of Hepatic Transforming Growth Factor-beta1 at the Early Stage of Hepatocellular Carcinoma Formation / 4(3): 91-96 / by Zhizhen Dong, Dengfu Yao, Yilang Wang, Junjun Shen, Chongguo Zhang, Hua Huang, Liwei Qiu, Wei Wu, and Xinhua Wu ¡@ Anti-Angiogenic Therapeutic Drugs for Treatment of Human Cancer / 4(2): 37-45 / by Han-Chung Wu, Chia-Ting Huang, and De-Kuan Chang ¡@ Analysis of Cytotoxic Effects of Chemotherapeutic Agents on Lung and Small Intestinal Neuroendocrine Cell Lines / 4(2): 47-54 / by Jan Bornschein, Mark Kidd, Maximilian V. Malfertheiner, Ignat Drozdov, Roswitha Pfragner, and Irvin M. Modlin ¡@ Phosphatidylinositol 3-Kinase and NF-kB Involved in Epidermal Growth Factor-Induced Matrix Metalloproteinase-9 Expression / 4(2): 55-60 / by Shuvojit Moulik, Triparna Sen, Anindita Dutta, Aniruddha Banerji, Chinmoy Ghosh, Shamik Das, and Amitava Chatterjee ¡@ Mesenchymal Stem Cells and Cancer ¡X for Better or for Worse? / 4(1): 5-9 / by B. Linju Yen and Men-Luh Yen ¡@ Curcumin: a Potential Cancer Chemopreventive Agent through Suppressing NF-kB Signaling / 4(1): 11-16 / by Chih-Li Lin and Jen-Kun Lin ¡@ Proteins Expressed on Tumor Endothelial Cells as Potential Targets for Anti-Angiogenic Therapy / 4(1): 17-22 / by Han-Chung Wu and Pi-Chun Li ¡@ Clinical Response of Gefitinib on Malignant Pleural Effusions in Patients with Non-Small Cell Lung Cancer / 4(1): 23-28 / by Chi-Hsien Chen, Chien-Hung Gow, Chong-Jen Yu, Jin-Yuan Shih, Ya-Chieh Hsu, Wen-Yu Lee, Pan-Chyr Yang, and Sow-Hsong Kuo ¡@ Epigenetic Regulation of EpCAM in Tumor Invasion and Metastasis / 3(6): 165-168 / by Shine-Gwo Shiah, Kang-Yu Tai, and Cheng-Wen Wu ¡@ Expression and Prognostic Significance of EpCAM / 3(6): 169-174 / by Philip Went, Stephan Dirnhofer, Daniel Schöpf, Holger Moch, and Gilbert Spizzo ¡@ Serum Levels of Apolipoprotein A-II as a Potential Marker for Cholangiocarcinoma / 3(6): 175-181 / by Xiaomin Wang, Anjian Xu, Bo Liu, Juling Wang, Liyun Liu, Songwei Dai, Xueyuan Xiao, and Dacheng He [Comment on this paper] ¡@ MicroRNA: A New Player in Breast Cancer Development / 3(5): 133-138 / by Vivien Wang and Wei Wu ¡@ Intercalating and Antitumour Activity of 4-Oxopyrimido[4',5':4,5]thieno(2,3-b)-quinoline-4(3H)-one / 3(5): 139-146 / by M. S. Shahabuddin, M. Gopal, and Sathees C. Raghavan ¡@ Anti-tumor Effect of Doxycycline on Glioblastoma Cells / 3(5): 147-153 / by Andrea Wang-Gillam, Eric Siegel, Debra A. Mayes, Laura F. Hutchins, and Yi-Hong Zhou ¡@ Targeted mTOR in Human Gynecologic Cancers / 3(4): 101-106 / by Yi-Jen Chen ¡@ Elevation of Serum HSP90alpha Correlated with the Clinical Stage of Non-Small Cell Lung Cancer / 3(4): 107-112 / by Anjian Xu, Tian Tian, Jia Hao, Jifu Liu, Zhao Zhang, Juanting Hao, Shanshan Wu, Lingyun Huang, Xueyuan Xiao, and Dacheng He ¡@ Insulin and Epidermal Growth Factor¡¦s Activation of Extracellular-Signal Regulated Kinases 1/2 and DNA Synthesis Is Inhibited by Four Cardiac Hormones / 3(4): 113-120 / by Ying Sun, Ehrentraud J. Eichelbaum, Hai Wang, and David L. Vesely ¡@ Curcumin and Quercetin Combined with Cisplatin to Induce Apoptosis in Human Laryngeal Carcinoma Hep-2 Cells through the Mitochondrial Pathway / 3(4): 121-128 / by Meenakshi Kuhar, Sabiha Imran, and Neeta Singh [Comment on this paper] ¡@ Cancer as a "Mitochondriopathy" / 3(3): 71-79 / by Anna M Czarnecka, Antonella Marino Gammazza, Valentina Di Felice, Giovanni Zummo, and Francesco Cappello ¡@ Induction of FADD Expression and Caspase Cascades Involved in RC-RNase-Induced Apoptosis in Human Cervical Cancer Cells / 3(3): 81-89 / by Huey-Chung Huang, You-Di Liao, Li-Li Chen, and Tze-Sing Huang ¡@ RNA Interference against MDR1 but not MRP1 Reverses Drug Resistance in Human Small-Cell Lung Cancer Cells / 3(3): 91-94 / by David Sadava and Wendy Hamman ¡@ Targeting the Nrf2-Prx1 Pathway with Selenium to Enhance the Efficacy and Selectivity of Cancer Therapy / 3(2): 37-43 / by Yun-Jeong Kim, Sun-Hee Baek, Paul N. Bogner, Clement Ip, Youcef M. Rustum, Marwan G. Fakih, Nithya Ramnath, and Young-Mee Park ¡@ The Role of Enolase in Tissue Invasion and Metastasis of Pathogens and Tumor Cells / 3(2): 45-48 / by Ko-Jiunn Liu and Neng-Yao Shih ¡@ In Vivo Effects of Cyclooxygenase-2 Deletion on Cellular Signaling in Hepatocellular Carcinoma Xenografts in Nude Mice / 3(2): 49-54 / by Wei Cui, Shirley X Hu, Zhen-Ya Tang, and Ke-Qin Hu ¡@ Dendritic Cells Pulsed with Irradiated Prostate Tumor Cells Express CC Receptor-7 and Its Ligands and Initiate a Tumor Specific Immune Response / 3(2): 55-60 / by Prabir K. Chakravarty, Giridhar R. Gorla, Zoya Niazova, and Bhadrasain Vikram ¡@ Lysosomal Cysteine Proteinase Cathepsin S as a Potential Target for Anti-Cancer Therapy / 3(1) 5-14 / by Wun-Shaing W. Chang, Hsin-Ru Wu, Chi-Tai Yeh, Cheng-Wen Wu, and Jang-Yang Chang ¡@ Antitumor Activity of Combination Treatment of Lentinus edodes Mycelium Extracts with 5-Fluorouracil against Human Colon Cancer Cells Xenografted in Nude Mice / 3(1) 15-22 / by Chih-Hsiung Wu, Chi-Chen Wu, and Yuan-Soon Ho ¡@ Effects of Platinum Derivatives on the Function and Expression of P-Glycoprotein/MDR1 in LLC-PK1 Cells: In the Cases of Carboplatin and Nedaplatin / 3(1) 23-28 / by Noriaki Kitada, Kohji Takara, Masayuki Tsujimoto, Toshiyuki Sakaeda, Noriaki Ohnishi, and Teruyoshi Yokoyama ¡@ Glioblastoma in a Patient with Professional Exposure to the Oncogenic Polyomavirus SV40 / 3(1) 29-32 / by Fernanda Martini, Veronica Balatti, Francesco Lupidi, Massimo Gerosa, and Mauro Tognon |
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